Products for Research Use Only
RegisterLogin

TIC10g

CAT: 0013-GTR19236504-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19236504-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TIC10g is a dual TLR7 and TLR9 inhibitor that suppresses TNF-α release in mouse macrophages and human B cells. It blocks NF-κB and MAPK activation, demonstrating anti-inflammatory potential for research in autoimmune diseases like lupus and rheumatoid arthritis.
CAS Number
754998-88-4
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
N=1C=C (C=2C=CC=3OCOC3C2) N (C1NCC4=CC=C (OC) C=C4OC) C
Molecular Formula
C20H21N3O4
Molecular Weight
367.4
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5-(1,3-benzodioxol-5-yl)-N-(2,4-dimethoxybenzyl)-1-methyl-1H-imidazol-2-amine
CAS Number754998-88-4
PubChem CID1096525
IUPAC Name5-(1,3-benzodioxol-5-yl)-N-[(2,4-dimethoxyphenyl)methyl]-1-methylimidazol-2-amine
Molecular FormulaC20H21N3O4
Molecular Weight367.4
XLogP3.2
Topological Polar Surface Area66.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count27
Formal Charge0
Complexity482
SMILES
CN1C(=CN=C1NCC2=C(C=C(C=C2)OC)OC)C3=CC4=C(C=C3)OCO4
InChI
InChI=1S/C20H21N3O4/c1-23-16(13-5-7-17-19(8-13)27-12-26-17)11-22-20(23)21-10-14-4-6-15(24-2)9-18(14)25-3/h4-9,11H,10,12H2,1-3H3,(H,21,22)
InChIKey
AKQCUNWVVQYIIO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-(1,3-benzodioxol-5-yl)-N-(2,4-dimethoxybenzyl)-1-methyl-1H-imidazol-2-amine
CAS: 754998-88-4
CID: 1096525
Formula: C20H21N3O4
MW: 367.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight367.4
XLogP33.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass367.15320616
Monoisotopic Mass367.15320616
Topological Polar Surface Area66.8 Ų
Heavy Atom Count27
Formal Charge0
Complexity482
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19168390-01TIC10
GTR19159568-01TIC10
GTR17961120TIC100 Antibody
GTR19168156-01TIC10 Isomer
GTR17961121TIC110 Antibody
GTR17961129TIC40 Antibody
GTR18586071-01Tic40 Antibody
GTR17961332TIC20-IV Antibody
GTR17961123TIC20-I Antibody
GTR17961463TIC20-V Antibody

Alternative Products

CatalogName
HY-162649TIC10g

Popular Products