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PHTPP-1304

CAT: 0013-GTR19236249-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236249-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PHTPP-1304 is an AUTOTAC-based small molecule that potently degrades ERβ (DC50 ~2 nM) by inducing p62 self-oligomerization and forming p62/ERβ puncta to engage autophagy. This compound is a valuable chemical probe for studying targeted protein degradation and autophagic flux in cellular models of cancer and endocrine research.
CAS Number
2410081-60-4
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (F) (F) (F) C=1N2C (=C (C (=N2) C3=CC=CC=C3) C4=CC=C (OCCOCCOCCNC[C@H] (COC5=CC (OCCCC6=CC=CC=C6) =C (OCC7=CC=CC=C7) C=C5) O) C=C4) N=C (C (F) (F) F) C1
Molecular Formula
C51H50F6N4O7
Molecular Weight
944.96
Storage Conditions
-20°C
Notes
For research use only.

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