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BDM19

CAT: 0013-GTR19235554-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235554-01Size:50 mg
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Description
BDM19 is a research compound that directly binds to and activates cytosolic BAX dimers, triggering apoptosis. It exhibits potent pro-apoptotic activity both as a single agent and in synergy with Navitoclax, a BCL-2/BCL-XL inhibitor, making it a valuable tool for studying mitochondrial apoptosis pathways in cancer research models, both in vitro and in vivo.
CAS Number
500273-31-4
Field of Research
Cell Biology
Smiles
O=C (O) C1=CC=C (C=C1) N2C (=O) C=3C=C (I) C=CC3N=C2C=CC4=CC=CC (=C4) C
Molecular Formula
C24H17IN2O3
Molecular Weight
508.31
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-[6-iodo-2-[(E)-2-(3-methylphenyl)ethenyl]-4-oxoquinazolin-3-yl]benzoic acid
CAS Number500273-31-4
PubChem CID6105914
IUPAC Name4-[6-iodo-2-[(E)-2-(3-methylphenyl)ethenyl]-4-oxoquinazolin-3-yl]benzoic acid
Molecular FormulaC24H17IN2O3
Molecular Weight508.3
XLogP5.1
Topological Polar Surface Area70
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count30
Formal Charge0
Complexity713
SMILES
CC1=CC(=CC=C1)/C=C/C2=NC3=C(C=C(C=C3)I)C(=O)N2C4=CC=C(C=C4)C(=O)O
InChI
InChI=1S/C24H17IN2O3/c1-15-3-2-4-16(13-15)5-12-22-26-21-11-8-18(25)14-20(21)23(28)27(22)19-9-6-17(7-10-19)24(29)30/h2-14H,1H3,(H,29,30)/b12-5+
InChIKey
CQEADRMBOXGOAE-LFYBBSHMSA-N
Chemical Structure
2D Structure
2D structure of 4-[6-iodo-2-[(E)-2-(3-methylphenyl)ethenyl]-4-oxoquinazolin-3-yl]benzoic acid
CAS: 500273-31-4
CID: 6105914
Formula: C24H17IN2O3
MW: 508.3
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight508.3
XLogP35.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass508.02839
Monoisotopic Mass508.02839
Topological Polar Surface Area70 Ų
Heavy Atom Count30
Formal Charge0
Complexity713
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T85816-01BDM19

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