Products for Research Use Only
RegisterLogin

COP1-ATGL modulator 1

CAT: 0013-GTR19235635-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19235635-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
COP1-ATGL modulator 1 (86) is a potent, orally bioavailable small molecule that targets the COP1-ATGL axis. It elevates ATGL levels, reduces its ubiquitination, and inhibits COP1 autoubiquitination, effectively diminishing hepatic lipid accumulation at nanomolar concentrations in vitro. This makes it a valuable research tool for studying NAFLD/NASH and metabolic disorders.
CAS Number
2946701-09-1
Field of Research
Metabolism Research
Purity
99.98% (May vary between batches)
Smiles
O=C (NC1=CC=CC (=C1) C (=O) C) NC2=CC=C3C (=C2) C (=O) N (C (=O) N3CCN4CCCCC4) CCOC
Molecular Formula
C27H33N5O5
Molecular Weight
507.58
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

COP1-ATGL modulator 1
CAS Number2946701-09-1
PubChem CID168952850
IUPAC Name1-(3-acetylphenyl)-3-[3-(2-methoxyethyl)-2,4-dioxo-1-(2-piperidin-1-ylethyl)quinazolin-6-yl]urea
Molecular FormulaC27H33N5O5
Molecular Weight507.6
XLogP1.8
Topological Polar Surface Area111
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count9
Heavy Atom Count37
Formal Charge0
Complexity832
SMILES
CC(=O)C1=CC(=CC=C1)NC(=O)NC2=CC3=C(C=C2)N(C(=O)N(C3=O)CCOC)CCN4CCCCC4
InChI
InChI=1S/C27H33N5O5/c1-19(33)20-7-6-8-21(17-20)28-26(35)29-22-9-10-24-23(18-22)25(34)32(15-16-37-2)27(36)31(24)14-13-30-11-4-3-5-12-30/h6-10,17-18H,3-5,11-16H2,1-2H3,(H2,28,29,35)
InChIKey
GPYDOCYVXSAKDL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of COP1-ATGL modulator 1
CAS: 2946701-09-1
CID: 168952850
Formula: C27H33N5O5
MW: 507.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight507.6
XLogP31.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count9
Exact Mass507.24816917
Monoisotopic Mass507.24816917
Topological Polar Surface Area111 Ų
Heavy Atom Count37
Formal Charge0
Complexity832
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR17964967Atgl-1 Antibody
GTR18236510-01COP1 Antibody
GTR18148891COP1 Antibody
GTR18008342COP1 Antibody
GTR18074344COP1 Antibody
GTR18914871COP1 Peptide
GTR18236511-01COP1 Antibody
GTR19176548-01NOT Receptor Modulator 1
GTR19240312-01α-Synuclein modulator 1
GTR19239643-01Gpr35 modulator 1

Alternative Products

CatalogName
HY-157416-01COP1-ATGL modulator 1
E8RT1058ATGL
311775-01COP1
10R-1132ATGL antibody
507064ATGL discontinued
45-306PATGL Peptide
342660-01COP1 discontinued
MBS8583261-01COP1 Antibody

Popular Products