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Enpp-1-IN-19

CAT: 0013-GTR19235400-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235400-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Enpp-1-IN-19 (compound 29f) is a potent, orally bioavailable ENPP1 inhibitor (IC50 = 68 nM) that suppresses cGAMP hydrolysis. It enhances STING signaling and type I interferon responses, improving anti-PD-1 therapy and tumor control in CT26 syngeneic mouse models while promoting protective immune memory against recurrence.
CAS Number
2738583-25-8
Field of Research
Immunology & Inflammation, Metabolism Research
Smiles
C (C=1C=2C (C (=O) N (C) N1) =CC=CC2) C3=CC=C (NS (N) (=O) =O) C=C3
Molecular Formula
C16H16N4O3S
Molecular Weight
344.39
Storage Conditions
-20°C
Notes
For research use only.

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