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Gcase activator 3

CAT: 0013-GTR19235334-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235334-02Size:5 mg
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Description
Gcase activator 3 is a small molecule that enhances glucocerebrosidase (GCase) activity, particularly in cellular models with GBA1 mutations. It serves as a valuable research tool for investigating lysosomal function and the pathogenesis of Parkinson's disease in both in vitro and in vivo experimental systems.
CAS Number
2270984-21-7
Field of Research
Metabolism Research
Purity
99.08% (May vary between batches)
Smiles
N (C[C@@H]1OC=2C (OC1) =CC=CC2) (C) C=3C4=C (N=C (N3) C=5C=CC=NC5) C=CC=C4
Molecular Formula
C23H20N4O2
Molecular Weight
384.43
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Gcase activator 3
CAS Number2270984-21-7
PubChem CID2527354
IUPAC NameN-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-N-methyl-2-pyridin-3-ylquinazolin-4-amine
Molecular FormulaC23H20N4O2
Molecular Weight384.4
XLogP4.1
Topological Polar Surface Area60.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count29
Formal Charge0
Complexity535
SMILES
CN(C[C@H]1COC2=CC=CC=C2O1)C3=NC(=NC4=CC=CC=C43)C5=CN=CC=C5
InChI
InChI=1S/C23H20N4O2/c1-27(14-17-15-28-20-10-4-5-11-21(20)29-17)23-18-8-2-3-9-19(18)25-22(26-23)16-7-6-12-24-13-16/h2-13,17H,14-15H2,1H3/t17-/m0/s1
InChIKey
JFOVNJQCUHRYOI-KRWDZBQOSA-N
Chemical Structure
2D Structure
2D structure of Gcase activator 3
CAS: 2270984-21-7
CID: 2527354
Formula: C23H20N4O2
MW: 384.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight384.4
XLogP34.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass384.15862589
Monoisotopic Mass384.15862589
Topological Polar Surface Area60.4 Ų
Heavy Atom Count29
Formal Charge0
Complexity535
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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