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HMC-B17

CAT: 0013-GTR19235245-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235245-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HMC-B17 is a potent, selective, and orally bioavailable HPK1 inhibitor (IC50 = 1.39 nM) that augments anti-PD-L1 therapy. It enhances T-cell function, evidenced by increased IL-2 secretion in Jurkat cells (EC50 = 11.56 nM), supporting its use in immuno-oncology research for investigating combination cancer therapies.
CAS Number
2935913-83-8
Field of Research
Signal Transduction
Smiles
O (C) C=1C=C (C=2C=3C (NC2) =NC=C (C3) C4=CC=C (C=C4) C5CCN (C) CC5) C=CC1OC
Molecular Formula
C27H29N3O2
Molecular Weight
427.54
Storage Conditions
-20°C
Notes
For research use only.

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