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JTT-654

CAT: 0013-GTR19235069-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235069-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JTT-654 is a potent, selective, and orally active inhibitor of 11β-HSD1, with low nanomolar IC50 values for human, rat, and mouse enzymes and high selectivity over 11β-HSD2. It functions as a competitive inhibitor and has been studied in research models for its potential to ameliorate insulin resistance and non-obese type 2 diabetes by targeting adipose and hepatic tissues.
CAS Number
916828-66-5
Field of Research
Metabolism Research
Smiles
C (=O) (C1=C (N (N=C1) C2CCN (C (=O) C3 (CO) CC3) CC2) C4CC4) N5C[C@@H] (CC5) C6=C (C (F) (F) F) C=CC=C6
Molecular Formula
C28H33F3N4O3
Molecular Weight
530.58
Storage Conditions
-20°C
Notes
For research use only.

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