Products for Research Use Only

NIC-12

CAT: 0013-GTR19234901-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234901-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NIC-12 is a selective NLRP3 inflammasome inhibitor. It effectively lowers plasma IL-1β in LPS-challenged mice and suppresses NLRP3 activation in murine macrophages, making it a valuable tool for studying inflammation in both in vivo endotoxemia models and in vitro cellular assays.
CAS Number
2409826-23-7
Field of Research
Immunology & Inflammation
Smiles
C (C) (C) C=1N2C3=C (C=C2C (=O) N (CC (N[C@H]4CN (CC5CC5) CCC4) =O) N1) SC (Cl) =C3
Molecular Formula
C22H28ClN5O2S
Molecular Weight
462.01
Storage Conditions
-20°C
Notes
For research use only.