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VZMC013

CAT: 0013-GTR19242401-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19242401-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VZMC013 is a potent chemical probe targeting the MOR-CCR5 heterodimer, which is implicated in opioid-exacerbated HIV-1 entry. It demonstrates nanomolar binding affinity, inhibits viral infection in TZM-bl and PBMC models, and is particularly effective in blocking opioid-accelerated HIV-1 entry, making it a valuable tool for neuroHIV and virology research.
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
O=C (COCC (NCCCCCCCNC (COCC (NCCC1=NN=C (C (C) C) N1[C@H]2C[C@H]3N (CC[C@H] (NC (C4CCC (F) (F) CC4) =O) C5=CC=CC=C5) [C@H] (CC3) C2) =O) =O) =O) N[C@H] (CC6) C7[C@] ([C@]6 (O) [C@H]8C9) (CCN8CC%10CC%10) C%11=C9C=CC (O) =C%11O7
Molecular Formula
C65H92F2N10O10
Molecular Weight
1211.48
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T202992-01VZMC013

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