Products for Research Use Only

NLRP3-IN-34

CAT: 0013-GTR19238073-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238073-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NLRP3-IN-34 (T10) is a potent small molecule inhibitor of the NLRP3 inflammasome, suppressing ROS generation, IL-1β production (IC50 = 0.48 μM in J774A.1 cells), and pyroptosis. It has demonstrated anti-inflammatory efficacy in vivo, validated in a DSS-induced peritonitis model using C57BL/6 mice, supporting its use in researching inflammatory and autoimmune diseases.
CAS Number
1392502-55-4
Field of Research
Cell Biology
Smiles
O=C (OC1C=2C=3C (=O) C (=O) C4=C (OC=C4C) C3C=CC2C (C) (C) CC1) C=5C=CC=CC5O
Molecular Formula
C26H22O6
Molecular Weight
430.45
Storage Conditions
-20°C
Notes
For research use only.