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LW1564

CAT: 0013-GTR19241880-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241880-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LW1564 is a small molecule HIF-1α inhibitor (IC50=1.2 μM in HepG2 cells) that suppresses mitochondrial respiration and activates AMPK, leading to reduced cancer cell proliferation (GI50 0.4-4.6 μM) and antitumor efficacy in xenograft models. It is a useful research tool for studying hypoxia signaling, cancer metabolism, and lipid synthesis pathways in vitro and in vivo.
CAS Number
2668337-39-9
Field of Research
Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Smiles
O=C (N1CCN (CC2=CC=C (C=C2) C (F) (F) F) CC1) COC3=CC=C (C=C3) C45CC6CC (CC (C (=O) N7CC8=CC (OC) =C (OC) C=C8CC7) (C6) C4) C5
Molecular Formula
C42H48F3N3O5
Molecular Weight
731.84
Storage Conditions
-20°C
Notes
For research use only.

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