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XL44

CAT: 0013-GTR19234658-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234658-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XL44 is a small molecule that binds hRpn13, inducing hRpn13-dependent apoptosis and reducing cell viability through a PCLAF-mediated mechanism. It promotes ubiquitin-dependent degradation of the hRpn13 Pru domain and ubiquitin-independent degradation of specific KEN box proteins. This compound is a valuable research tool for studying proteasome regulation, cell death pathways, and targeted protein degradation in both cellular and biochemical assays.
CAS Number
2637949-91-6
Field of Research
Cell Biology
Smiles
C (=C1C=2C (NC1=O) =CC=C (F) C2) C3=CC (NC (=O) C4=CC=C (OC) C=C4) =CC=C3
Molecular Formula
C23H17FN2O3
Molecular Weight
388.39
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-162393-01XL44

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