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AN5777

CAT: 0013-GTR19234005-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234005-01Size:25 mg
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Description
AN5777 is a small molecule that induces targeted degradation of GSPT1 via the ubiquitin-proteasome pathway. This action leads to cell cycle arrest in G1 phase, apoptosis, and demonstrates antitumor activity in research models, supporting its investigation in oncology and molecular biology studies.
CAS Number
491586-42-6
Field of Research
Cell Biology
Smiles
O=C (NN=CC=1C=CC=CC1O) C2=CC=3C=CC=C (C3N=C2C) C
Molecular Formula
C19H17N3O2
Molecular Weight
319.36
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N'-(2-hydroxybenzylidene)-2,8-dimethyl-3-quinolinecarbohydrazide
CAS Number491586-42-6
PubChem CID135435757
IUPAC NameN-[(E)-(2-hydroxyphenyl)methylideneamino]-2,8-dimethylquinoline-3-carboxamide
Molecular FormulaC19H17N3O2
Molecular Weight319.4
XLogP3.5
Topological Polar Surface Area74.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count24
Formal Charge0
Complexity468
SMILES
CC1=C2C(=CC=C1)C=C(C(=N2)C)C(=O)N/N=C/C3=CC=CC=C3O
InChI
InChI=1S/C19H17N3O2/c1-12-6-5-8-14-10-16(13(2)21-18(12)14)19(24)22-20-11-15-7-3-4-9-17(15)23/h3-11,23H,1-2H3,(H,22,24)/b20-11+
InChIKey
ARBAVLNDKREMOX-RGVLZGJSSA-N
Chemical Structure
2D Structure
2D structure of N'-(2-hydroxybenzylidene)-2,8-dimethyl-3-quinolinecarbohydrazide
CAS: 491586-42-6
CID: 135435757
Formula: C19H17N3O2
MW: 319.4
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight319.4
XLogP33.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass319.132076794
Monoisotopic Mass319.132076794
Topological Polar Surface Area74.6 Ų
Heavy Atom Count24
Formal Charge0
Complexity468
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T88210-01AN5777

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