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Pomalidomide 4'-alkylC6-azide

CAT: 0013-GTR19233120Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19233120Size:25 mg
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Description
Pomalidomide 4'-alkylC6-azide is a cereblon (CRBN) -directed ligand designed for PROTAC development. It serves as a key component for constructing bifunctional degraders, enabling targeted protein degradation studies in both cellular and biochemical research contexts.
CAS Number
2375555-72-7
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCCCCCN=[N+]=[N-]
Molecular Formula
C19H22N6O4
Molecular Weight
398.42
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Pomalidomide 4'-alkylC6-azide
CAS Number2375555-72-7
PubChem CID150423126
IUPAC Name4-(6-azidohexylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Molecular FormulaC19H22N6O4
Molecular Weight398.4
XLogP3.2
Topological Polar Surface Area110
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Heavy Atom Count29
Formal Charge0
Complexity719
SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCCCN=[N+]=[N-]
InChI
InChI=1S/C19H22N6O4/c20-24-22-11-4-2-1-3-10-21-13-7-5-6-12-16(13)19(29)25(18(12)28)14-8-9-15(26)23-17(14)27/h5-7,14,21H,1-4,8-11H2,(H,23,26,27)
InChIKey
HIFBXUYLIWPOBR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Pomalidomide 4'-alkylC6-azide
CAS: 2375555-72-7
CID: 150423126
Formula: C19H22N6O4
MW: 398.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight398.4
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Exact Mass398.17025320
Monoisotopic Mass398.17025320
Topological Polar Surface Area110 Ų
Heavy Atom Count29
Formal Charge0
Complexity719
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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