HA-14-1

CAT: 0013-GTR19232949-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19232949-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

HA-14-1 is a Bcl-2 surface pocket inhibitor (IC50 ~9 μM) that disrupts Bcl-2/Bak interactions, leading to Apaf-1-mediated caspase activation and apoptosis. It has demonstrated potent pro-apoptotic activity in vitro, such as in HL-60 acute myeloid leukemia cells. This small molecule is a useful research tool for studying mitochondrial apoptosis pathways in cancer models.

CAS Number

927635-64-1

Field of Research

Cell Biology

Smiles

C (C (OCC) =O) (C#N) C1C=2C (OC (N) =C1C (OCC) =O) =CC=C (Br) C2

Molecular Formula

C17H17BrN2O5

Molecular Weight

409.2

Storage Conditions

-20°C

Notes

For research use only.

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T84388-01	HA-14-1
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HA-14-1

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