Products for Research Use Only
RegisterLogin

JQKD82 dihydrochloride

CAT: 0013-GTR19232541Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19232541Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
JQKD82 (JADA82) dihydrochloride is a potent, cell-permeable KDM5 inhibitor that elevates global H3K4me3 levels. It is a valuable chemical probe for studying histone demethylase function in hematological cancers, including multiple myeloma, in both cellular and animal models.
CAS Number
2863635-05-4
Field of Research
Epigenetics & Chromatin
Smiles
O (C (=O) C=1C=C (CNCC (N (CCN (C) C) CC) =O) N=CC1) C2=C (OC (C) C) C=C (OC (C) C) C=C2.Cl
Molecular Formula
C27H42Cl2N4O5
Molecular Weight
573.55
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

CID 146374976
CAS Number2863635-05-4
PubChem CID146374976
IUPAC Name[2,4-di(propan-2-yloxy)phenyl] 2-[[[2-[2-(dimethylamino)ethyl-ethylamino]-2-oxoethyl]amino]methyl]pyridine-4-carboxylate
Molecular FormulaC27H40N4O5
Molecular Weight500.6
XLogP3.1
Topological Polar Surface Area93.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count15
Heavy Atom Count36
Formal Charge0
Complexity660
SMILES
CCN(CCN(C)C)C(=O)CNCC1=NC=CC(=C1)C(=O)OC2=C(C=C(C=C2)OC(C)C)OC(C)C
InChI
InChI=1S/C27H40N4O5/c1-8-31(14-13-30(6)7)26(32)18-28-17-22-15-21(11-12-29-22)27(33)36-24-10-9-23(34-19(2)3)16-25(24)35-20(4)5/h9-12,15-16,19-20,28H,8,13-14,17-18H2,1-7H3
InChIKey
APYABXFXNNTCQD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of CID 146374976
CAS: 2863635-05-4
CID: 146374976
Formula: C27H40N4O5
MW: 500.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight500.6
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count15
Exact Mass500.29987039
Monoisotopic Mass500.29987039
Topological Polar Surface Area93.2 Ų
Heavy Atom Count36
Formal Charge0
Complexity660
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19171435-01JQKD82
GTR19189140-01JQKD82 trihydrochloride
GTR19216470-01TMPD dihydrochloride
GTR19213627-01DPTN dihydrochloride
GTR19209925-01Fabomotizole dihydrochloride
GTR19209849-01Derazantinib dihydrochloride
GTR19209662-01Valbenazine dihydrochloride
GTR19209091-01ASP9436 Dihydrochloride
GTR19206095-01DB1976 dihydrochloride
GTR19205542-01LCL521 dihydrochloride

Alternative Products

CatalogName
T84915-01JQKD82 dihydrochloride
HY-138691BJQKD82 (dihydrochloride)
MBS3616808-01JQKD82
HY-138691A-01JQKD82 (trihydrochloride)
MBS5800346JQKD82 trihydrochloride
408145JQKD82 HCl
OR1013406-01Formamidine disulfide dihydrochloride Disulfide Dihydrochloride
A15150-2Merestinib dihydrochloride (LY2801653 dihydrochloride) 2mg
MBS130300-01Mirodenafil-dihydrochloride, SK-3530 dihydrochloride
A21622-50Iadademstat dihydrochloride (ORY-1001 dihydrochloride) 50mg

Popular Products