AF615

CAT: 0013-GTR19231892-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19231892-01Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

AF615 is a potent small-molecule disruptor of the CDT1/Geminin interaction, exhibiting IC50 values of 0.313 μM. This compound demonstrates selective genotoxic effects in cancer cells, including DNA synthesis inhibition, cell cycle arrest, and reduced viability. Binding studies reveal differential affinity for protein variants (Ki = 0.37 μM for Geminin-tCDT1 vs 0.75 μM for Geminin-miniCDT1) .

CAS Number

122510-61-6

Purity

>98%

Smiles

O1CCN (C (=S) NNC (C2=CN=CC=N2) =O) CC1

Molecular Formula

C10H13N5O2S

Molecular Weight

267.307

Notes

For research use only.