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Tesirine

CAT: 0013-GTR19231541-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19231541-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MP-PEG8-VA-PABC-PBD Dimer is a drug-linker conjugate designed for antibody-drug conjugates (ADCs) . Its PBD dimer payload acts as a potent DNA alkylating agent, inhibiting DNA replication. This compound is used in cancer research for developing ADCs and has been evaluated in both in vitro cytotoxicity assays and in vivo xenograft models.
CAS Number
1595275-62-9
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
[H][C@@]12CC (C) =CN1C (=O) c1cc (OC) c (OCCCCCOc3cc4N ([C@@H] (O) [C@]5 ([H]) CC (C) =CN5C (=O) c4cc3OC) C (=O) OCc3ccc (NC (=O) [C@H] (C) NC (=O) [C@@H] (NC (=O) CCOCCOCCOCCOCCOCCOCCOCCOCCNC (=O) CCN4C (=O) C=CC4=O) C (C) C) cc3) cc1N=C2
Molecular Formula
C75H101N9O23
Molecular Weight
1496.65
Storage Conditions
-20°C
Notes
For research use only.

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