Tesirine

• Target :

  Drug-Linker Conjugates for ADC|||DNA Alkylator/Crosslinker

• Related Pathways :

  DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

• Bioactivity :

  MP-PEG8-VA-PABC-PBD Dimer is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1].

• Smiles :

  [H][C@@]12CC(C)=CN1C(=O)c1cc(OC)c(OCCCCCOc3cc4N([C@@H](O)[C@]5([H])CC(C)=CN5C(=O)c4cc3OC)C(=O)OCc3ccc(NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN4C(=O)C=CC4=O)C(C)C)cc3)cc1N=C2

• Molecular Formula :

  C75H101N9O23

• Molecular Weight :

  1496.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1595275-62-9