Products for Research Use Only

SA-VA

CAT: 0013-GTR19230471-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230471-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SA-VA is an intracellular self-assembling PROTAC designed for the selective degradation of VEGFR-2 and EphB4. It is activated in situ via a copper-catalyzed click reaction utilizing endogenous tumor copper, inducing S-phase cell cycle arrest and apoptosis in U87 glioblastoma cells for targeted cancer research.
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C50H53ClF3N11O7S
Molecular Weight
1044.54
Storage Conditions
-20°C
Notes
For research use only.