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Antileishmanial agent-21

CAT: 0013-GTR19230394-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230394-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antileishmanial agent-21 (compound 4e) is a potent inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1) via an anti-folate mechanism, with activity reversible by folic acid. It also inhibits chloroquine-resistant Plasmodium falciparum (RKL9 strain) with low nanomolar IC50 values. This compound is a valuable tool for investigating folate metabolism in parasitic diseases through in vitro enzymatic and cellular assays.
Field of Research
Infectious Disease & Virology
Molecular Formula
C21H16N2O3
Molecular Weight
344.36
Storage Conditions
-20°C
Notes
For research use only.

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