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PI3Kα/HDAC6-IN-1

CAT: 0013-GTR19230332-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230332-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3Kα/HDAC6-IN-1 is a potent dual inhibitor of PI3Kα (IC50=2.9 nM) and HDAC6 (IC50=26 nM) . It suppresses AKT phosphorylation and increases acetylated α-tubulin, demonstrating strong anti-proliferative activity in vitro, such as against multiple myeloma L-363 cells (IC50=0.17 μM), making it a valuable research tool for oncology and signaling pathway studies.
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Molecular Formula
C27H30F3N7O6S2
Molecular Weight
669.7
Storage Conditions
-20°C
Notes
For research use only.

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