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PHD-IN-1

CAT: 0013-GTR19230255-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230255-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PHD-IN-1 (compound 80) is a highly potent PHD2 inhibitor with an IC50 of ≤5 nM. It induces EPO expression with an EC50 of 2.5 μM in cellular assays, as demonstrated in Caco2 and Hep3B cell lines. This inhibitor is a valuable chemical probe for researching hypoxia signaling pathways in both cellular and animal models of HIF stabilization.
CAS Number
2924182-31-8
Field of Research
Epigenetics & Chromatin, Metabolism Research
Smiles
OC=1C2=C (N=C (N3[C@@]4 (CN ([C@] (C3) (C4) [H]) C5CC5) [H]) C=C2) C=NC1C (NCC=6C=CC (C#N) =NC6) =O
Molecular Formula
C24H23N7O2
Molecular Weight
441.49
Storage Conditions
-20°C
Notes
For research use only.

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