C-Fms-IN-14

CAT: 0013-GTR19230238-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19230238-01Size:5 mg

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Description

C-Fms-IN-14 (Example 76) is a highly potent, selective c-Fms/CSF1R kinase inhibitor with a 4 nM IC50. It is a valuable research tool for investigating the role of CSF1R signaling in oncology and immunology, supporting both in vitro cellular assays and in vivo disease model studies.

CAS Number

1898210-99-5

Field of Research

Signal Transduction

Smiles

NC1=C2N (C3=C (C2=NC=N1) CCC3) C4=CC=C (NC (CC=5C=C6C (=CC5) N (C) C=C6) =O) C=C4

Molecular Formula

C26H24N6O

Molecular Weight

436.51

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

c-Fms-IN-14

CAS Number	1898210-99-5
PubChem CID	121265862
IUPAC Name	N-[4-(9-amino-7,10,12-triazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9,11-tetraen-7-yl)phenyl]-2-(1-methylindol-5-yl)acetamide
Molecular Formula	C26H24N6O
Molecular Weight	436.5
XLogP	3.2
Topological Polar Surface Area	90.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Heavy Atom Count	33
Formal Charge	0
Complexity	711

SMILES

CN1C=CC2=C1C=CC(=C2)CC(=O)NC3=CC=C(C=C3)N4C5=C(CCC5)C6=C4C(=NC=N6)N

InChI

InChI=1S/C26H24N6O/c1-31-12-11-17-13-16(5-10-21(17)31)14-23(33)30-18-6-8-19(9-7-18)32-22-4-2-3-20(22)24-25(32)26(27)29-15-28-24/h5-13,15H,2-4,14H2,1H3,(H,30,33)(H2,27,28,29)

InChIKey

XLGIACOJUXWECZ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1898210-99-5

CID: 121265862

Formula: C26H24N6O

MW: 436.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	436.5
XLogP3	3.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	436.20115941
Monoisotopic Mass	436.20115941
Topological Polar Surface Area	90.8 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	711
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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GTR19243931-01	C-Fms-IN-13
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GTR19206355-01	C-Fms-IN-10
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Alternative Products

Catalog	Name
HY-156556	C-Fms-IN-14
308416-01	C-Fms
M35575-01	C-Fms-IN-13
BA8846-10	c-Fms-IN-12
BA8851-5.1	c-Fms-IN-1
BA8857-1	c-Fms-IN-8
CLC51750-01	C-Fms-in-10
T10649-01	C-Fms-IN-3
386597	C-Fms discontinued
MBS3614754-01	c-Fms-IN-2

C-Fms-IN-14

Chemical Information

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