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P-gp inhibitor 14

CAT: 0013-GTR19234795-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234795-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Compound 8a (P-gp inhibitor 14) is a potent, high-affinity P-glycoprotein inhibitor with an EC50 of 48.74 nM, effectively reversing multidrug resistance in vitro. It shows minimal CYP3A4 inhibition and is a valuable research tool for studying drug efflux and chemosensitization in cancer models.
CAS Number
2892571-47-8
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O (C) C=1C2=C (C=3C=4C5=C (C (OC) =CC4CN (CC3C1) C6=CC=C (CCN7CC=8C (CC7) =CC (OC) =C (OC) C8) C=C6) OCO5) OCO2
Molecular Formula
C37H38N2O8
Molecular Weight
638.71
Storage Conditions
-20°C
Notes
For research use only.

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