Products for Research Use Only
RegisterLogin

SHEN26

CAT: 0013-GTR19234644-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19234644-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SHEN26 (ATY014) is an orally bioavailable 5’-cyclohexanecarboxylate derivative of GS-441524, functioning as a potent SARS-CoV-2 RdRp inhibitor (IC50 = 1.36 μM) to block viral RNA replication. It demonstrates antiviral activity in both cellular assays and animal models, supporting its use in COVID-19 therapeutic research.
CAS Number
2691076-98-7
Field of Research
Infectious Disease & Virology
Smiles
C (#N) [C@]1 (O[C@H] (COC (=O) C2CCCCC2) [C@@H] (O) [C@H]1O) C=3N4C (=CC3) C (N) =NC=N4
Molecular Formula
C19H23N5O5
Molecular Weight
401.42
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Losudesivir
CAS Number2691076-98-7
PubChem CID162513663
IUPAC Name[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methyl cyclohexanecarboxylate
Molecular FormulaC19H23N5O5
Molecular Weight401.4
XLogP0.7
Topological Polar Surface Area156
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Heavy Atom Count29
Formal Charge0
Complexity665
SMILES
C1CCC(CC1)C(=O)OC[C@@H]2[C@H]([C@H]([C@](O2)(C#N)C3=CC=C4N3N=CN=C4N)O)O
InChI
InChI=1S/C19H23N5O5/c20-9-19(14-7-6-12-17(21)22-10-23-24(12)14)16(26)15(25)13(29-19)8-28-18(27)11-4-2-1-3-5-11/h6-7,10-11,13,15-16,25-26H,1-5,8H2,(H2,21,22,23)/t13-,15-,16-,19+/m1/s1
InChIKey
NJZZWWHRMAGFGB-ZIGSKRJUSA-N
Chemical Structure
2D Structure
2D structure of Losudesivir
CAS: 2691076-98-7
CID: 162513663
Formula: C19H23N5O5
MW: 401.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight401.4
XLogP30.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass401.16991885
Monoisotopic Mass401.16991885
Topological Polar Surface Area156 Ų
Heavy Atom Count29
Formal Charge0
Complexity665
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19187002-01Sheng Gelieting
GTR18014484SHE2 Antibody
GTR18014483SHE2 Antibody
GTR18014367SHE2 Antibody
GTR18014482SHE2 Antibody
GTR18014204SHE2 Antibody
GTR18014369SHE2 Antibody
GTR18014205SHE2 Antibody

Alternative Products

CatalogName
T87387-01SHEN26

Popular Products