Sulfathiazole (sodium)

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CAT:

804-HY-B0507A-01

Size:

500 mg

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Sulfathiazole (sodium)

CAS Number: 144-74-1
UNSPSC Description: Sulfathiazole sodium is an organosulfur compound that has been used as a short-acting sulfa drug. Target: Antibacterial Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3) [1]. Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level [2]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species [3].
Target Antigen: Antibiotic; Bacterial
Type: Reference compound
Related Pathways: Anti-infection
Applications: COVID-19-immunoregulation
Field of Research: Infection
Assay Protocol: https://www.medchemexpress.com/Sulfathiazole-sodium.html
Purity: 99.92
Solubility: DMSO : 140 mg/mL (ultrasonic)|H2O : 140 mg/mL (ultrasonic)
Smiles: O=S(C1=CC=C(N)C=C1)([N-]C2=NC=CS2)=O.[Na+]
Molecular Weight: 277.30
References & Citations: [1]Perez, S., P. Eichhorn, and D.S. Aga, Evaluating the biodegradability of sulfamethazine, sulfamethoxazole, sulfathiazole, and trimethoprim at different stages of sewage treatment. Environ Toxicol Chem, 2005. 24(6): p. 1361-7.|[2]Haller, M.Y., et al., Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. J Chromatogr A, 2002. 952(1-2): p. 111-20.|[3]Kahle, M. and C. Stamm, Time and pH-dependent sorption of the veterinary antimicrobial sulfathiazole to clay minerals and ferrihydrite. Chemosphere, 2007. 68(7): p. 1224-31.Research Square Preprint. 2021 Aug.|Chemosphere. 2019 Jun;225:378-387. |Theranostics. 2022 Jan 1;12(3):1187-1203.
Shipping Conditions: Room Temperature
Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
Clinical Information: Launched

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Cat	Name
HY-B0507A-02	Sulfathiazole (sodium)
HY-B0507A-03	Sulfathiazole (sodium)
HY-B0507A-01	Sulfathiazole (sodium)
HY-B0507-02	Sulfathiazole
HY-B0507-03	Sulfathiazole
HY-B0507-01	Sulfathiazole
HY-B0507R	Sulfathiazole (Standard)
HY-B0507S	Sulfathiazole-d4
HY-B0507B	Sulfathiazole (100 µg/mL in acetonitrile)
HY-131410	Sinoporphyrin (sodium)