Products for Research Use Only

SR 11023

CAT: 0013-GTR19234616-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234616-01Size:10 mg
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Description
SR 11023 is a potent and orally bioavailable PPARγ antagonist with an IC50 of 109 nM. It is a valuable research tool for studying insulin resistance and type 2 diabetes in both cellular assays and animal models.
CAS Number
1820602-13-8
Field of Research
Metabolism Research, Molecular Biology
Smiles
C (N1C=2C (=CC (C (N[C@@H] (C) C3=CC (=CC=C3) C4CC4) =O) =CC2) C (C) =C1C) C5=CC=C (C (C (O) =O) (C) C) C=C5
Molecular Formula
C33H36N2O3
Molecular Weight
508.65
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-[4-[[5-[[(1S)-1-(3-cyclopropylphenyl)ethyl]carbamoyl]-2,3-dimethylindol-1-yl]methyl]phenyl]-2-methylpropanoic acid
CAS Number1820602-13-8
PubChem CID71478927
IUPAC Name2-[4-[[5-[[(1S)-1-(3-cyclopropylphenyl)ethyl]carbamoyl]-2,3-dimethylindol-1-yl]methyl]phenyl]-2-methylpropanoic acid
Molecular FormulaC33H36N2O3
Molecular Weight508.6
XLogP6.8
Topological Polar Surface Area71.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count8
Heavy Atom Count38
Formal Charge0
Complexity845
SMILES
CC1=C(N(C2=C1C=C(C=C2)C(=O)N[C@@H](C)C3=CC=CC(=C3)C4CC4)CC5=CC=C(C=C5)C(C)(C)C(=O)O)C
InChI
InChI=1S/C33H36N2O3/c1-20-22(3)35(19-23-9-14-28(15-10-23)33(4,5)32(37)38)30-16-13-27(18-29(20)30)31(36)34-21(2)25-7-6-8-26(17-25)24-11-12-24/h6-10,13-18,21,24H,11-12,19H2,1-5H3,(H,34,36)(H,37,38)/t21-/m0/s1
InChIKey
DVWSHWWLAFDNHD-NRFANRHFSA-N
Chemical Structure
2D Structure
2D structure of 2-[4-[[5-[[(1S)-1-(3-cyclopropylphenyl)ethyl]carbamoyl]-2,3-dimethylindol-1-yl]methyl]phenyl]-2-methylpropanoic acid
CAS: 1820602-13-8
CID: 71478927
Formula: C33H36N2O3
MW: 508.6
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight508.6
XLogP36.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count8
Exact Mass508.27259301
Monoisotopic Mass508.27259301
Topological Polar Surface Area71.3 Ų
Heavy Atom Count38
Formal Charge0
Complexity845
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes