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PROTAC IRAK4 degrader-1

CAT: 0013-GTR19226849-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19226849-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC IRAK4 degrader-1 (I-210) is a heterobifunctional degrader that links an IRAK4-targeting ligand to the Cereblon recruiter Pomalidomide via an AM-Imidazole-PA-Boc linker. This compound facilitates the targeted ubiquitination and proteasomal degradation of IRAK4, serving as a valuable chemical probe for studying IRAK4 biology and oncology research in cellular models.
CAS Number
2360533-90-8
Product Name Alternative
PROTAC IRAK4 degrader1, PROTAC IRAK-4 degrader-1, PROTAC IRAK4 degrader-1, PROTAC IRAK4 degrader 1
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.76% (May vary between batches)
Solubility
DMSO:160 mg/mL (176.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.53 mM)
Smiles
O=C (NC1=CN (N=C1C (F) (F) F) C2=CC=C (C=C2) C (=O) NCCCN3C=NC (=C3) CNC4=CC=CC=5C (=O) N (C (=O) C45) C6C (=O) NC (=O) CC6) C=7N=C (OC7) C=8C=CN=C (C8) NCC9CC9
Molecular Formula
C44H39F3N12O7
Molecular Weight
904.85
Storage Conditions
-20°C
Notes
For research use only.

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