L-159282

CAT: 0013-GTR19226480-02Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19226480-02Size:50 mg

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Description

L-159282 is a nonpeptide, orally bioavailable antagonist of the angiotensin II receptor, demonstrating antihypertensive effects. It is utilized in cardiovascular research to study hypertension mechanisms and has been employed in both in vitro binding assays and in vivo animal models of blood pressure regulation.

CAS Number

157263-00-8

Field of Research

Metabolism Research

Smiles

O=C (NS (=O) (=O) C=1C=CC=CC1C2=CC=C (C=C2) CN3C4=NC (=CC (=C4N=C3CC) C) C) C=5C=CC=CC5

Molecular Formula

C30H28N4O3S

Molecular Weight

524.63

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

MK 996

an AT1-selective angiotensin II receptor antagonist; structure given in first source

CAS Number	157263-00-8
PubChem CID	133031
IUPAC Name	N-[2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]phenyl]sulfonylbenzamide
Molecular Formula	C30H28N4O3S
Molecular Weight	524.6
XLogP	5.9
Topological Polar Surface Area	102
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Heavy Atom Count	38
Formal Charge	0
Complexity	894

SMILES

CCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC(=O)C5=CC=CC=C5)N=C(C=C2C)C

InChI

InChI=1S/C30H28N4O3S/c1-4-27-32-28-20(2)18-21(3)31-29(28)34(27)19-22-14-16-23(17-15-22)25-12-8-9-13-26(25)38(36,37)33-30(35)24-10-6-5-7-11-24/h5-18H,4,19H2,1-3H3,(H,33,35)

InChIKey

LIUNMFCWFYFUGQ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 157263-00-8

CID: 133031

Formula: C30H28N4O3S

MW: 524.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	524.6
XLogP3	5.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Exact Mass	524.18821194
Monoisotopic Mass	524.18821194
Topological Polar Surface Area	102 Å²
Heavy Atom Count	38
Formal Charge	0
Complexity	894
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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HY-19191	L-159282
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A20703-50	L-159282 50mg
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A20703-5	L-159282 5mg
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453216-01	L-Arginyl-L-valyl-L-α-aspartyl-L-prolyl-L-valyl-L-asparaginyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine

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Chemical Information

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