L-159282

CAT: 0804-HY-19191Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-19191Size:1 Each

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Description

L-159282 is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity.

CAS Number

157263-00-8

Product Name Alternative

MK 996

UNSPSC

12352005

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/L-159282.html

Solubility

10 mM in DMSO

Smiles

O=C(NS(=O)(C1=CC=CC=C1C2=CC=C(CN3C(CC)=NC4=C(C)C=C(C)N=C43)C=C2)=O)C5=CC=CC=C5

Molecular Formula

C30H28N4O3S

Molecular Weight

524.63

References & Citations

[1]Kivlighn SD, et al. In vivo pharmacology of a novel AT1 selective angiotensin II receptor antagonist, MK-996. Am J Hypertens. 1995 Jan;8 (1) :58-66.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

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Catalog	Name
MBS5769257	L-159282
A20703-10	L-159282 10mg
A20703-50	L-159282 50mg
A20703-1	L-159282 1mg
A20703-5	L-159282 5mg
CCP1053-01	A-L-A-L
453309-01	L-Glycyl-L-lysyl-L-leucyl-L-isoleucyl-L-tyrosyl-L-seryl-L-alanyl-L-seryl-L-phenylalanyl-L-leucyl-L-tyrosyl-L-seryl-L-glycyl-L-valyl-L-prolyl-L-seryl-L-arganine
453434-01	L-Seryl-L-threonyl-L-glycyl-L-isoleucyl-L-seryl-L-valyl-L-prolyl-L-glycyl-L-prolyl-L-methionyl-L-glycyl-L-prolyl-L-seryl-L-glycyl-L-prolyl-L-Arginine
JH918176	L-Arginine, L-valyl-L-seryl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginylglycylglycyl-L-arginyl-L-arginyl-L-arginyl-
453216-01	L-Arginyl-L-valyl-L-α-aspartyl-L-prolyl-L-valyl-L-asparaginyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine

L-159282

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