Products for Research Use Only

Mal-PEG2-NH2

CAT: 0013-GTR19226375-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19226375-01Size:100 mg
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Description
Mal-PEG2-NH2 is a heterobifunctional PEG linker used to construct PROTAC molecules for targeted protein degradation. It connects a target-binding ligand to an E3 ligase recruiter, enabling the study of protein function in both cellular and animal models through the ubiquitin-proteasome system.
CAS Number
660843-22-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C1C=CC (=O) N1CCOCCOCCN
Molecular Formula
C10H16N2O4
Molecular Weight
228.25
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione
CAS Number660843-22-1
PubChem CID22377694
IUPAC Name1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]pyrrole-2,5-dione
Molecular FormulaC10H16N2O4
Molecular Weight228.24
XLogP-1.8
Topological Polar Surface Area81.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Heavy Atom Count16
Formal Charge0
Complexity260
SMILES
C1=CC(=O)N(C1=O)CCOCCOCCN
InChI
InChI=1S/C10H16N2O4/c11-3-5-15-7-8-16-6-4-12-9(13)1-2-10(12)14/h1-2H,3-8,11H2
InChIKey
SHDYDABQVJGHLD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione
CAS: 660843-22-1
CID: 22377694
Formula: C10H16N2O4
MW: 228.24
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight228.24
XLogP3-1.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Exact Mass228.11100700
Monoisotopic Mass228.11100700
Topological Polar Surface Area81.9 Ų
Heavy Atom Count16
Formal Charge0
Complexity260
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes