N-Me-Thalidomide-NH-C6-NH2

N-Me-Thalidomide-NH-C6-NH2

• CAS Number: 2375536-48-2
• UNSPSC Description: N-Me-Thalidomide-NH-C6-NH2 is an E3 ligase ligand-linker conjugate. N-Me-Thalidomide-NH-C6-NH2 can be used to synthesize Anti-inflammatory agent 70 (HY-157570)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n-me-thalidomide-nh-c6-nh2.html
• Smiles: NCCCCCCNC1=C2C(C(N(C2=O)C3CCC(N(C3=O)C)=O)=O)=CC=C1
• Molecular Weight: 386.44
• References & Citations: [1]Jin Liu, et al. Novel CRBN-Recruiting Proteolysis-Targeting Chimeras as Degraders of Stimulator of Interferon Genes with In Vivo Anti-Inflammatory Efficacy. Journal of Medicinal Chemistry. 2022 65 (9), 6593-6611
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported