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Collagenase, Type VI

CAT: 0804-HY-E70005I-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-E70005I-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Collagenase, Type VI (EC 3.4.24.3) is a collagenase that can degrade type VI collagen. Type VI collagen is a component of cell membranes in various tissues (such as skin, heart, blood vessels, cartilage, and synovial fluid) . Excessive collagenase can cause extracellular matrix lesions. Collagenase is also a biomarker for tumor invasion and metastasis. Collagenase, Type VI can specifically act on the peptide bond between proline and glycine. This feature can be used to quickly and sensitively detect its concentration level in experiments using corresponding modified electrodes[1].
CAS Number
9001-12-1
Product Name Alternative
Type VI collagenase
UNSPSC
12352204
Target
MMP
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/collagenase-type-vi.html
Solubility
H2O : ≥ 50 mg/mL
Smiles
[Collagenase,TypeVI]
References & Citations
[1]Dong ZM, et al. Amplified QCM biosensor for type IV collagenase based on collagenase-cleavage of gold nanoparticles functionalized peptide. Biosens Bioelectron. 2018 May 30;106:111-116.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported

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