Products for Research Use Only
RegisterLogin

MS143

CAT: 0013-GTR19221350Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19221350Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MS143 is a potent and selective AKT degrader with a DC50 of 46 nM in PC3 cells. It induces targeted protein degradation via the ubiquitin-proteasome system, suppressing cancer cell proliferation in vitro. This molecule is a valuable chemical probe for studying AKT-dependent signaling pathways in oncology research.
CAS Number
2376137-41-4
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) CCCCCCCCCCC (=O) N2CCN (CC[C@H] (NC (=O) C3 (N) CCN (CC3) c3ncnc4[nH]ccc34) c3ccc (Cl) cc3) CC2) C (C) (C) C) cc1
Molecular Formula
C59H81ClN12O6S
Molecular Weight
1121.87
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19175746-01MS1943
GTR19262991-01MS147
GTR19096543-01Recombinant Mannheimia succiniciproducens UPF0756 membrane protein MS1439 (MS1439)

Alternative Products

CatalogName
MBS5816278MS143

Popular Products