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JPS036

CAT: 0013-GTR19221225Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221225Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JPS036 is a VHL-based PROTAC that selectively degrades class I HDACs, primarily HDAC1/2. This degradation induces widespread gene expression changes and promotes apoptosis in cellular models like HCT116, supporting its use in oncology and epigenetics research.
CAS Number
2669785-85-5
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) C2 (F) CC2) C (C) (C) C) c (OCCCCCCCCCCCC (=O) Nc2ccc (cc2) C (=O) Nc2ccccc2N) c1
Molecular Formula
C51H66FN7O7S
Molecular Weight
940.18
Storage Conditions
-20°C
Notes
For research use only.

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