Products for Research Use Only
RegisterLogin

Angiogenesis inhibitor 3

CAT: 0013-GTR19221082-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19221082-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Angiogenesis Inhibitor 3 is a potent small molecule with in vitro activity, inhibiting HUVEC and HCT-15 cell growth (IC50 1.00 and 0.71 μM) and invasion while inducing apoptosis. It also demonstrates in vivo antiangiogenic efficacy in zebrafish embryo models, supporting its use in cancer and angiogenesis research.
CAS Number
2507759-39-7
Field of Research
Cardiovascular Research; Pharmacology & Drug Discovery, Cell Biology
Smiles
[H][C@]12Cc3ccc (Oc4cc (C[C@]5 ([H]) N (C) CCc6c (Br) c (OC) c (OC (=O) c7ccccc7) c (Oc7cc1c (CCN2C) cc7OC) c56) c (cc4OC) N (=O) =O) cc3
Molecular Formula
C44H42BrN3O9
Molecular Weight
836.72
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Angiogenesis inhibitor 3
CAS Number2507759-39-7
PubChem CID164517120
IUPAC Name[(1S,14S)-19-bromo-9,20,25-trimethoxy-15,30-dimethyl-11-nitro-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18(33),19,21,24,26,31-dodecaen-21-yl] benzoate
Molecular FormulaC44H42BrN3O9
Molecular Weight836.7
XLogP8.6
Topological Polar Surface Area125
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count11
Rotatable Bond Count6
Heavy Atom Count57
Formal Charge0
Complexity1360
SMILES
CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=C(C(=C5)C[C@H]6C7=C(CCN6C)C(=C(C(=C7O3)OC(=O)C8=CC=CC=C8)OC)Br)[N+](=O)[O-])OC)OC
InChI
InChI=1S/C44H42BrN3O9/c1-46-17-15-27-21-35(52-3)38-23-31(27)33(46)19-25-11-13-29(14-12-25)55-37-22-28(32(48(50)51)24-36(37)53-4)20-34-39-30(16-18-47(34)2)40(45)42(54-5)43(41(39)56-38)57-44(49)26-9-7-6-8-10-26/h6-14,21-24,33-34H,15-20H2,1-5H3/t33-,34-/m0/s1
InChIKey
MLOAMUYYMSJIRP-HEVIKAOCSA-N
Chemical Structure
2D Structure
2D structure of Angiogenesis inhibitor 3
CAS: 2507759-39-7
CID: 164517120
Formula: C44H42BrN3O9
MW: 836.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight836.7
XLogP38.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count11
Rotatable Bond Count6
Exact Mass835.21044
Monoisotopic Mass835.21044
Topological Polar Surface Area125 Ų
Heavy Atom Count57
Formal Charge0
Complexity1360
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19234189-01Angiogenesis inhibitor 6
GTR19218434-01Angiogenesis inhibitor 4
GTR19208508-01Angiogenesis inhibitor BT2
GTR18810863-01Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit
GTR18850560-01Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit
GTR19221409-01Angiogenesis agent 1
GTR18774951Angiogenesis Antibody Panel
GTR19213615-01GSK-3 inhibitor 3
GTR19192053-01GSK-3β inhibitor 3
GTR19244108-01GSK-3β inhibitor 3

Alternative Products

CatalogName
TRC-A637973-50MGAngiogenesis Inhibitor
T83116-01Angiogenesis inhibitor 4
HY-170916Angiogenesis inhibitor 7
T88027-01Angiogenesis inhibitor 6
HY-147891Angiogenesis inhibitor 3
HY-147890Angiogenesis inhibitor 2
T71722-01Angiogenesis inhibitor BT2
TBI4010-250MGUrsolic acid, Angiogenesis Inhibitor
TBI1399-5MGBorrelidin, Threonyl-tRNA synthase inhibitor; Angiogenesis inhibitor
AP80882-01Brain-specific angiogenesis inhibitor 3

Popular Products