Products for Research Use Only
RegisterLogin

(±) -Evodiamine

CAT: 0013-GTR19220432-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19220432-01Size:1 ml x 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(±) -Evodiamine is a natural topoisomerase I inhibitor that suppresses adipogenesis and inflammation via modulation of IGF-1/HIF-1α, IL-6/STAT, and NF-κB pathways. It has been studied in vitro and in vivo for its roles in inhibiting cancer cell invasion, promoting apoptosis, and blocking TNF-induced Akt activation.
CAS Number
518-18-3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.90% (May vary between batches)
Solubility
DMSO:8 mg/mL (26.37 mM) ;10% DMSO+90% Corn Oil:0.5 mg/mL (1.65 mM)
Smiles
CN1C2C3=C (C=4C (N3) =CC=CC4) CCN2C (=O) C=5C1=CC=CC5
Molecular Formula
C19H17N3O
Molecular Weight
303.36
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Isoevodiamine

LSM-6483 is a member of beta-carbolines.

CAS Number518-18-3
PubChem CID151289
IUPAC Name21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one
Molecular FormulaC19H17N3O
Molecular Weight303.4
XLogP3.1
Topological Polar Surface Area39.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Heavy Atom Count23
Formal Charge0
Complexity495
SMILES
CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3
InChI
InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3
InChIKey
TXDUTHBFYKGSAH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Isoevodiamine
CAS: 518-18-3
CID: 151289
Formula: C19H17N3O
MW: 303.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight303.4
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass303.137162174
Monoisotopic Mass303.137162174
Topological Polar Surface Area39.3 Ų
Heavy Atom Count23
Formal Charge0
Complexity495
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19228848-01Evonimine

Alternative Products

CatalogName
N1600-200Evodiamine
MBS5817346(+/-)-Evodiamine
HY-N0114A-01(±) -Evodiamine
OR1030825-01(?-Evodiamine

Popular Products