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PROTAC BRD4 Degrader-9

CAT: 0013-GTR19222215-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19222215-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC BRD4 Degrader-9 is a heterobifunctional degrader that links ligands for VHL and BRD4, inducing potent degradation of BRD4 in PC3 cells. Its antibody-conjugated forms, targeting STEAP1 and CLL1, show high potency with DC50 values of 0.86 nM and 7.6 nM, respectively, supporting research in targeted protein degradation for oncology.
CAS Number
2417370-42-2
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@H] (CN2C (=O) [C@@H] (NC (=O) COCCOCCOCCNC (=O) c2cc3N (Cc4c[nH]c5c4c (cn (C) c5=O) -c3cc2CS (C) (=O) =O) c2ncc (F) cc2F) C (C) (C) C) OC (=O) OCC (C) (C) SS (C) (=O) =O) cc1
Molecular Formula
C59H71F2N9O15S4
Molecular Weight
1312.5
Storage Conditions
-20°C
Notes
For research use only.

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