Products for Research Use Only

LL-K8-22

CAT: 0013-GTR19220931-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19220931-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LL-K8-22 is a potent and selective dual degrader of CDK8-cyclin C, with DC50 values around 2.5 μM. It suppresses STAT1 S727 phosphorylation and inhibits oncogenic E2F/MYC transcriptional programs. This compound is a research tool for studying triple-negative breast cancer (TNBC) in both cellular and animal models.
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Molecular Formula
C37H43N5O
Molecular Weight
573.77
Storage Conditions
-20°C
Notes
For research use only.