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GNE-4997

CAT: 0013-GTR19226509-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19226509-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNE-4997 is a highly potent and selective ITK inhibitor with a Ki of 0.09 nM. Its optimized basicity profile reduces off-target antiproliferative effects, lowering cytotoxicity. This compound is a valuable research tool for studying T-cell signaling in immunological and inflammatory disease models, both in vitro and in vivo.
CAS Number
1705602-02-3
Field of Research
Signal Transduction
Smiles
C[C@@]12[C@@] (C1 (F) F) (CC3=C (C2) NN=C3C (NC4=CN ([C@@H] ([C@@]5 (S (=O) (=O) CCCC5) [H]) C6=CC=CC=C6) N=C4) =O) [H]
Molecular Formula
C25H27F2N5O3S
Molecular Weight
515.58
Storage Conditions
-20°C
Notes
For research use only.

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T15402-01GNE-4997
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