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HP661

CAT: 0013-GTR19219856-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219856-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HP661 is a potent and selective mitochondrial complex I inhibitor that reduces viability in OXPHOS-high lung cancer cells (e.g., H460, A549) with nanomolar IC50s while sparing low-OXPHOS cells. It demonstrates significant in vivo antitumor activity in an H460 xenograft model and synergizes with trametinib, supporting its use in cancer metabolism and therapy resistance research.
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FC (F) (F) C1=CC=C (NC (C2=CC=C (CN3N=NC (C (N4CCN (CC5=CC=C (OCC (F) (F) F) C=C5) CC4) =O) =C3C) C=N2) =O) C=C1
Molecular Formula
C31H29F6N7O3
Molecular Weight
661.60
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T83865-01HP661

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