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TH-Z835

CAT: 0013-GTR19219500-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219500-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TH-Z835 is a mutant-selective inhibitor of KRAS (G12D) with an IC50 of 1.6 μM. It functions by blocking the nucleotide exchange activity of the oncogenic protein. This compound is a valuable research tool for investigating KRAS-driven cancers in both cellular and biochemical assays.
CAS Number
2766209-50-9
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O (C[C@H]1N (C) CCC1) C2=NC (=C3C (CN (CC3) C=4C5=C (C=CC4) C=CC=C5C) =N2) N6CC7NC (C6) CC7
Molecular Formula
C30H38N6O
Molecular Weight
498.66
Storage Conditions
-20°C
Notes
For research use only.

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