T-0156

CAT: 0013-GTR19219469-02Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19219469-02Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

T-0156 is a selective PDE5 inhibitor that potently prevents cGMP hydrolysis with minimal off-target activity against other PDE families. This research compound is utilized in vitro and in vivo to study cGMP signaling pathways relevant to cardiovascular physiology and erectile dysfunction.

CAS Number

324572-92-1

Product Name Alternative

CGMP, PDE1, PDE2, PDE3, PDE5, T 0156, T0156free

Field of Research

Infectious Disease & Virology, Metabolism Research

Purity

98.53% (May vary between batches)

Solubility

DMSO:55 mg/mL (94.24 mM)

Smiles

O=C (OC) C1=C (C=2C=C (OC) C (OC) =C (OC) C2) C=3C=CN=C (OCC4=NC=CC=N4) C3C (=O) N1CC=5C=CN=C (C5) C

Molecular Formula

C31H29N5O7

Molecular Weight

583.59

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

T0156

2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylic acid methyl ester is a naphthyridine derivative.

CAS Number	324572-92-1
PubChem CID	5368
IUPAC Name	methyl 2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylate
Molecular Formula	C31H29N5O7
Molecular Weight	583.6
XLogP	2.5
Topological Polar Surface Area	135
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	11
Heavy Atom Count	43
Formal Charge	0
Complexity	978

SMILES

CC1=NC=CC(=C1)CN2C(=C(C3=C(C2=O)C(=NC=C3)OCC4=NC=CC=N4)C5=CC(=C(C(=C5)OC)OC)OC)C(=O)OC

InChI

InChI=1S/C31H29N5O7/c1-18-13-19(7-11-32-18)16-36-27(31(38)42-5)25(20-14-22(39-2)28(41-4)23(15-20)40-3)21-8-12-35-29(26(21)30(36)37)43-17-24-33-9-6-10-34-24/h6-15H,16-17H2,1-5H3

InChIKey

JEMJAABFSYOLAP-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 324572-92-1

CID: 5368

Formula: C31H29N5O7

MW: 583.6

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	583.6
XLogP3	2.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	11
Exact Mass	583.20669828
Monoisotopic Mass	583.20669828
Topological Polar Surface Area	135 Å²
Heavy Atom Count	43
Formal Charge	0
Complexity	978
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
GTR19163431-01	AZD-0156
GTR19185492-01	EB-0156
GTR18219984-01	Rabbit 4E-T/eIF4E-T Antibody
GTR19198913-01	T-3256336
GTR19196384-01	T-226296
GTR19196383-01	T-3364366
GTR19185753-01	BCP-T.A
GTR19281123-01	T-02
GTR19274110-01	T-1228
GTR19263435-01	T-271

Alternative Products

Catalog	Name
BUP03208-01	T-0156
B5162-10	T 0156 hydrochloride
532801	T-0156 hydrochloride
HY-164685-01	T-0156 (free base)
B1305-25	AZD-0156
MBS5805845	EB-0156
TRC-A216040-75MG	AZD 0156
E11-124117	Insulin (Clone 0156) Mouse mAb
ABL-TC0651	T.T
042546	T, NT (T, Brachyury protein, Protein T)

T-0156

Chemical Information

Related Products

Alternative Products

Popular Products