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YN14

CAT: 0013-GTR19219163-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219163-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YN14 is a potent and selective KRASG12C-targeting PROTAC that effectively degrades the oncoprotein by recruiting the VHL E3 ligase. It demonstrates robust antiproliferative activity in vitro and induces tumor regression in vivo, as evidenced in MIA PaCa-2 xenograft models with high tumor growth inhibition rates.
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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