Products for Research Use Only
RegisterLogin

PROTAC IRAK4 ligand-3

CAT: 0013-GTR19218640-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19218640-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PROTAC IRAK4 Ligand-3 is a key component of the heterobifunctional degrader PROTAC IRAK4 Degrader-7. This small molecule is applied in oncology research to investigate IRAK4 degradation, with utility in both in vitro cellular assays and in vivo preclinical studies for cancers driven by IRAK4 signaling.
CAS Number
2434848-46-9
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (NC=1C (C (F) F) =NN (C1) [C@@H]2CC[C@@H] (C=O) CC2) (=O) C3=C4N (C=CC (=N4) N5[C@@]6 (C[C@] (C5) (OC6) [H]) [H]) N=C3
Molecular Formula
C23H25F2N7O3
Molecular Weight
485.49
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

PROTAC IRAK4 ligand-3
CAS Number2434848-46-9
PubChem CID146598958
IUPAC NameN-[3-(difluoromethyl)-1-(4-formylcyclohexyl)pyrazol-4-yl]-5-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Molecular FormulaC23H25F2N7O3
Molecular Weight485.5
XLogP1.1
Topological Polar Surface Area107
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Heavy Atom Count35
Formal Charge0
Complexity801
SMILES
C1CC(CCC1C=O)N2C=C(C(=N2)C(F)F)NC(=O)C3=C4N=C(C=CN4N=C3)N5C[C@H]6C[C@@H]5CO6
InChI
InChI=1S/C23H25F2N7O3/c24-21(25)20-18(10-32(29-20)14-3-1-13(11-33)2-4-14)27-23(34)17-8-26-31-6-5-19(28-22(17)31)30-9-16-7-15(30)12-35-16/h5-6,8,10-11,13-16,21H,1-4,7,9,12H2,(H,27,34)/t13?,14?,15-,16-/m1/s1
InChIKey
FONMEYJFOROCKC-QDIHITRGSA-N
Chemical Structure
2D Structure
2D structure of PROTAC IRAK4 ligand-3
CAS: 2434848-46-9
CID: 146598958
Formula: C23H25F2N7O3
MW: 485.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight485.5
XLogP31.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass485.19869401
Monoisotopic Mass485.19869401
Topological Polar Surface Area107 Ų
Heavy Atom Count35
Formal Charge0
Complexity801
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19240454-01PROTAC IRAK4 ligand-4
GTR19240546-01PROTAC IRAK4 ligand-5
GTR19222237-01PROTAC IRAK4 degrader-3
GTR19226849-01PROTAC IRAK4 degrader-1
GTR19222240-01PROTAC IRAK4 degrader-5
GTR19221536-01PROTAC IRAK4 degrader-2
GTR19240201-01PROTAC IRAK4 degrader-12
GTR19234058-01PROTAC IRAK4 degrader-10
GTR19264215-01PROTAC IRAK4 degrader-13
GTR19262646-01PROTAC IRAK4 degrader-11

Alternative Products

CatalogName
T81378-01PROTAC IRAK4 ligand-3
HY-129967-01PROTAC IRAK4 ligand-1
HY-168311PROTAC IRAK4 ligand-5
HY-168611PROTAC IRAK4 ligand-4
MBS5800292PROTAC IRAK4 degrader-3
T211884-01PROTAC IRAK4 degrader-13
T88159-01PROTAC IRAK4 degrader-10
T39901-01PROTAC IRAK4 degrader-4
MBS5820758PROTAC IRAK4 degrader-8
BUP21150-01PROTAC IRAK4 degrader-1

Popular Products