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MS83

CAT: 0013-GTR19218524-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218524-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MS83 is a bifunctional PROTAC molecule designed for targeted protein degradation. It links a ligand for the E3 ligase adapter KEAP1 to a BRD4/3/2 inhibitor, facilitating the ubiquitination and proteasomal degradation of these BET proteins. This tool compound is utilized in vitro and in vivo to study BET protein function and PROTAC mechanisms in oncology and disease models.
CAS Number
2762181-19-9
Field of Research
Pharmacology & Drug Discovery
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCC (NCCOC4=C5C (=CC ([C@@H] (CC (OCC) =O) C6=CC (CN7S (=O) (=O) C=8C (O[C@H] (C) C7) =CC=CC8) =C (C) C=C6) =C4) N=NN5C) =O) =O) N=C2C9=CC=C (Cl) C=C9) =NN=C3C) SC1C
Molecular Formula
C52H55ClN10O8S2
Molecular Weight
1047.64
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T81746-01MS83
T208150-01MS83 epimer 1

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