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Estrogen receptor modulator 10

CAT: 0013-GTR19217595-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19217595-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Compound G-5b is a potent estrogen receptor antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM) that induces apoptosis and G1/G0 cell cycle arrest. Its mechanism supports research into ER-positive cancers, such as breast cancer, in both cellular and animal model studies.
CAS Number
2991504-90-4
Field of Research
Cell Biology, Metabolism Research, Protein Biochemistry
Smiles
C (C (CO) (F) F) N1[C@@H] (C2=C (C=3C (N2) =CC=CC3) C[C@H]1C) C4=C (F) C=C (NC5CN (CCCS (CCCC (C (F) (F) F) (F) F) (=O) =O) C5) C=C4F
Molecular Formula
C32H37F9N4O3S
Molecular Weight
728.71
Storage Conditions
-20°C
Notes
For research use only.

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