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Protostemonine

CAT: 0013-GTR19217309-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19217309-01Size:100 mg
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Description
Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro-inflammatory mediators, such as iNOS, NO and cytokines. Protostemonine shows strong nematicidal activity against Panagrellus redivevus, with the IC50 value of 0.10 uM.Protostemonine attenuates LPS/GalN-induced acute liver failure and upregulating HO-1 expression is implicated in its hepatoprotective activity. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration.
CAS Number
27495-40-5
Purity
>98% (HPLC)
Smiles
CC1CC (OC1=O) C2CCC3N2CCCC4C3C (C (=C5C (=C (C (=O) O5) C) OC) O4) C
Molecular Formula
C23H31NO6
Molecular Weight
417.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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